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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP4
All Species:
36.06
Human Site:
Y245
Identified Species:
56.67
UniProt:
Q02790
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02790
NP_002005.1
459
51805
Y245
P
P
N
A
E
L
K
Y
E
L
H
L
K
S
F
Chimpanzee
Pan troglodytes
XP_508927
414
47057
V228
K
L
E
Q
S
T
I
V
K
E
R
G
T
V
Y
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
Y245
P
P
N
A
E
L
K
Y
E
L
H
L
K
S
F
Dog
Lupus familis
XP_534923
459
51500
Y245
P
P
N
A
E
L
K
Y
E
I
H
L
K
S
F
Cat
Felis silvestris
Mouse
Mus musculus
P30416
458
51554
Y245
P
P
H
A
E
L
R
Y
E
V
R
L
K
S
F
Rat
Rattus norvegicus
Q9QVC8
458
51432
Y245
P
P
H
A
E
L
R
Y
E
V
H
L
K
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
E233
M
D
T
K
E
K
L
E
Q
A
A
I
V
K
E
Chicken
Gallus gallus
NP_001006250
442
50413
Y238
P
P
D
A
E
L
Q
Y
E
V
K
L
K
S
F
Frog
Xenopus laevis
NP_001084916
447
50310
Y241
P
P
G
A
E
L
Q
Y
D
I
R
L
K
S
F
Zebra Danio
Brachydanio rerio
NP_958877
449
50474
Y240
P
P
N
A
T
L
Q
Y
K
I
K
M
K
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
W241
C
G
K
G
L
E
E
W
K
L
S
D
E
E
R
Honey Bee
Apis mellifera
XP_395748
459
51510
L241
E
K
V
E
V
W
S
L
K
N
H
E
Q
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
Y234
K
V
K
S
K
Y
A
Y
G
S
Q
G
K
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
Y245
P
P
H
A
E
L
R
Y
E
V
H
L
K
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
L252
A
V
P
P
N
A
T
L
E
I
N
L
E
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
98.4
91.7
N.A.
89.7
89.9
N.A.
46.4
74.7
66
61.2
N.A.
41.3
47.7
N.A.
45.9
Protein Similarity:
100
90.1
99.5
97.5
N.A.
95.4
95.2
N.A.
65.3
86
80.6
82.1
N.A.
61
64.4
N.A.
64
P-Site Identity:
100
0
100
93.3
N.A.
73.3
80
N.A.
6.6
73.3
66.6
53.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
100
N.A.
20
93.3
86.6
86.6
N.A.
33.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
89.9
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
95.2
N.A.
45
N.A.
N.A.
P-Site Identity:
N.A.
80
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
60
0
7
7
0
0
7
7
0
0
14
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
0
7
0
0
7
0
0
7
% D
% Glu:
7
0
7
7
60
7
7
7
54
7
0
7
14
7
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% F
% Gly:
0
7
7
7
0
0
0
0
7
0
0
14
0
0
0
% G
% His:
0
0
20
0
0
0
0
0
0
0
40
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
27
0
7
0
7
0
% I
% Lys:
14
7
14
7
7
7
20
0
27
0
14
0
67
7
0
% K
% Leu:
0
7
0
0
7
60
7
14
0
20
0
60
0
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
27
0
7
0
0
0
0
7
7
0
0
0
0
% N
% Pro:
60
60
7
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
20
0
7
0
7
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
20
0
0
0
7
% R
% Ser:
0
0
0
7
7
0
7
0
0
7
7
0
0
54
0
% S
% Thr:
0
0
7
0
7
7
7
0
0
0
0
0
7
0
0
% T
% Val:
0
14
7
0
7
0
0
7
0
27
0
0
7
7
7
% V
% Trp:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
67
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _